173D
MULTIPLE BINDING MODES OF ANTICANCER DRUG ACTINOMYCIN D: X-RAY, MOLECULAR MODELING, AND SPECTROSCOPIC STUDIES OF D(GAAGCTTC)2-ACTINOMYCIN D COMPLEXES AND ITS HOST DNA
Summary for 173D
| Entry DOI | 10.2210/pdb173d/pdb |
| Related | 172D 1A7Y 1A7Z 1DSC 1DSD 1FJA 1I3W 1L1V 1MNV 1OVF 1QFI 1UNJ 1UNM 209D 2D55 316D |
| Related PRD ID | PRD_000001 |
| Descriptor | DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3'), ACTINOMYCIN D (3 entities in total) |
| Functional Keywords | actinomycin, antibiotic, antitumor, anticancer, chromophore, depsipeptide, dna-antibiotic complex, dna/antibiotic |
| Biological source | STREPTOMYCES ANTIBIOTICUS |
| Total number of polymer chains | 4 |
| Total formula weight | 7372.13 |
| Authors | Kamitori, S.,Takusagawa, F. (deposition date: 1994-04-18, release date: 1994-10-15, Last modification date: 2023-11-15) |
| Primary citation | Kamitori, S.,Takusagawa, F. Multiple Binding Modes of Anticancer Drug Actinomycin D: X-Ray, Molecular Modeling, and Spectroscopic Studies of D(Gaagcttc)2-Actinomycin D Complexes and its Host DNA J.Am.Chem.Soc., 116:4154-, 1994 Cited by DOI: 10.1021/JA00089A002PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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