9ZFO
Cryo-EM Structure of Human STAT2-USP18-ISG15 Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (U) | Ubl carboxyl-terminal hydrolase 18 | polymer | 347 | 40401.7 | 1 | UniProt (Q9UMW8) | Homo sapiens (human) | 43 kDa ISG15-specific protease,hUBP43,ISG15-specific-processing protease,Ubl thioesterase 18 |
| 2 | B (S) | Signal transducer and activator of transcription 2 | polymer | 713 | 82825.8 | 1 | UniProt (P52630) | Homo sapiens (human) | p113 |
| 3 | C (I) | Ubiquitin-like protein ISG15 | polymer | 157 | 17147.6 | 1 | UniProt (P05161) | Homo sapiens (human) | Interferon-induced 15 kDa protein,Interferon-induced 17 kDa protein,IP17,Ubiquitin cross-reactive protein,hUCRP |
Sequence modifications
I: 1 - 157 (UniProt: P05161)
| PDB | External Database | Details |
|---|---|---|
| Ser 78 | Cys 78 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 140375.2 | |
| All* | Total formula weight | 140375.2 |
