9Y70

Cryo-EM structure of ML-SA1-bound full-length mouse TRPML2 channel in lipid nanodisc, closed I

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Mucolipin-2	polymer	566	65520.6	4	UniProt (Q8K595) Pfam (PF21381) Pfam (PF08016)	Mus musculus (house mouse)	Transient receptor potential channel mucolipin 2,TRPML2
2	E, F, G, H (A, B, C, D)	2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione	non-polymer		362.4	4	Chemie (AQV) PubChem (1364417)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	262082.4
Non-Polymers*	Number of molecules	4
	Total formula weight	1449.7
All*	Total formula weight	263532.1

*Water molecules are not included.