9VL2
Structure of CD33 complexed with its mAb-10C8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Myeloid cell surface antigen CD33 | polymer | 214 | 23990.0 | 2 | UniProt (P20138) Pfam (PF07686) Pfam (PF00047) | Homo sapiens (human) | Sialic acid-binding Ig-like lectin 3,Siglec-3,gp67 |
| 2 | B, E (B, E) | light chain of Fab-10C8 | polymer | 213 | 23439.0 | 2 | Homo sapiens (human) | ||
| 3 | C, F (C, F) | heavy chain of Fab-10C8 | polymer | 220 | 23127.8 | 2 | Homo sapiens (human) | ||
| 4 | G, H (G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | I, J, K, L (A, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) PubChem (24139) |
Sequence modifications
A, D: 18 - 231 (UniProt: P20138)
| PDB | External Database | Details |
|---|---|---|
| Leu 96 | Pro 96 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 141113.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 142847.5 |
