9OU8
Crystal structure of hUGDH Dimer-A104L/A136M complexed with UDP-Xyl
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | UDP-glucose 6-dehydrogenase | polymer | 464 | 51833.2 | 2 | UniProt (O60701) | Homo sapiens (human) | UDP-Glc dehydrogenase,UDP-GlcDH,UDPGDH |
| 2 | C, E (A, B) | URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE | non-polymer | 536.3 | 2 | Chemie (UDX) | |||
| 3 | D, F (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) PubChem (1061) | |||
| 4 | G (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 274 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 466 (UniProt: O60701)
| PDB | External Database | Details |
|---|---|---|
| Leu 104 | Ala 104 | engineered mutation |
| Met 136 | Ala 136 | engineered mutation |
| Asp 323 | Phe 323 | engineered mutation |
| - | Asn 324 | deletion |
| Asp 325 | Thr 325 | engineered mutation |
| Val 327 | Thr 327 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 103666.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1324.6 | |
| All* | Total formula weight | 104990.9 |
