9OJM
Human mitochondrial 28S PIC with tRNA and mtIF2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (0) | Small ribosomal subunit protein mS34 | polymer | 215 | 25336.1 | 1 | UniProt (P82930) | Homo sapiens (human) | 28S ribosomal protein S34,mitochondrial,MRP-S34,S34mt |
| 2 | B (1) | Small ribosomal subunit protein mS35 | polymer | 278 | 32156.9 | 1 | UniProt (P82673) | Homo sapiens (human) | 28S ribosomal protein S28,mitochondrial,MRP-S28,S28mt,28S ribosomal protein S35,MRP-S35,S35mt |
| 3 | C (2) | Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 | polymer | 118 | 13498.8 | 1 | UniProt (Q96BP2) | Homo sapiens (human) | 28S ribosomal protein S37,mitochondrial,MRP-S37,Mitochondrial small ribosomal subunit protein mS37,Nuclear protein C2360 |
| 4 | D (3) | Small ribosomal subunit protein mS38 | polymer | 71 | 8936.9 | 1 | UniProt (Q9NWT8) | Homo sapiens (human) | 28S ribosomal protein S38,mitochondrial,MRP-S38,Aurora kinase A-interacting protein,AURKA-interacting protein |
| 5 | E (4) | Small ribosomal subunit protein mS39 | polymer | 616 | 70984.2 | 1 | UniProt (Q96EY7) | Homo sapiens (human) | 28S ribosomal protein S39,mitochondrial,MRP-S39,Pentatricopeptide repeat domain-containing protein 3,Transformation-related gene 15 protein,TRG-15 |
| 6 | F (5) | RNA (71-MER) | polymer | 71 | 22664.5 | 1 | GenBank (1896813686) | Homo sapiens | |
| 7 | G (6) | mRNA (5'-R(P*AP*UP*GP*U)-3') | polymer | 4 | 1241.8 | 1 | Homo sapiens | ||
| 8 | H (7) | Translation initiation factor IF-2, mitochondrial | polymer | 571 | 63169.2 | 1 | UniProt (P46199) | Homo sapiens (human) | IF-2(Mt),IF-2Mt,IF2(mt) |
| 9 | I (A) | 12S mitochondrial RNA | polymer | 955 | 306547.5 | 1 | GenBank (1858621102) | Homo sapiens (human) | |
| 10 | J (B) | Small ribosomal subunit protein uS2m | polymer | 225 | 25988.9 | 1 | UniProt (Q9Y399) | Homo sapiens (human) | 28S ribosomal protein S2,mitochondrial,MRP-S2,S2mt |
| 11 | K (C) | 28S ribosomal protein S24, mitochondrial | polymer | 132 | 15333.8 | 1 | UniProt (Q96EL2) | Homo sapiens (human) | S24mt,Mitochondrial small ribosomal subunit protein uS3m,bMRP-47,bMRP47 |
| 12 | L (D) | 28S ribosomal protein S5, mitochondrial | polymer | 343 | 38919.0 | 1 | UniProt (P82675) | Homo sapiens (human) | S5mt,Mitochondrial small ribosomal subunit protein uS5m |
| 13 | M (E) | 28S ribosomal protein S6, mitochondrial | polymer | 122 | 13861.0 | 1 | UniProt (P82932) | Homo sapiens (human) | S6mt,Mitochondrial small ribosomal subunit protein bS6m |
| 14 | N (F) | 28S ribosomal protein S7, mitochondrial | polymer | 208 | 24569.8 | 1 | UniProt (Q9Y2R9) | Homo sapiens (human) | S7mt,Mitochondrial small ribosomal subunit protein uS7m,bMRP-27a,bMRP27a |
| 15 | O (G) | Small ribosomal subunit protein uS9m | polymer | 344 | 40136.1 | 1 | UniProt (P82933) | Homo sapiens (human) | 28S ribosomal protein S9,mitochondrial,MRP-S9,S9mt |
| 16 | P (H) | Small ribosomal subunit protein uS10m | polymer | 140 | 16361.0 | 1 | UniProt (P82664) | Homo sapiens (human) | 28S ribosomal protein S10,mitochondrial,MRP-S10,S10mt |
| 17 | Q (I) | Small ribosomal subunit protein uS11m | polymer | 137 | 14509.8 | 1 | UniProt (P82912) | Homo sapiens (human) | 28S ribosomal protein S11,mitochondrial,MRP-S11,S11mt,Cervical cancer proto-oncogene 2 protein,HCC-2 |
| 18 | R (J) | 28S ribosomal protein S12, mitochondrial | polymer | 108 | 12013.2 | 1 | UniProt (O15235) | Homo sapiens (human) | S12mt,MT-RPS12,Mitochondrial small ribosomal subunit protein uS12m |
| 19 | S (K) | 28S ribosomal protein S14, mitochondrial | polymer | 101 | 12282.3 | 1 | UniProt (O60783) | Homo sapiens (human) | S14mt,Mitochondrial small ribosomal subunit protein uS14m |
| 20 | T (L) | Small ribosomal subunit protein uS15m | polymer | 174 | 20729.5 | 1 | UniProt (P82914) | Homo sapiens (human) | 28S ribosomal protein S15,mitochondrial,MRP-S15,S15mt |
| 21 | U (M) | Small ribosomal subunit protein bS16m | polymer | 119 | 13438.7 | 1 | UniProt (Q9Y3D3) | Homo sapiens (human) | 28S ribosomal protein S16,mitochondrial,MRP-S16,S16mt |
| 22 | V (N) | Small ribosomal subunit protein uS17m | polymer | 110 | 12349.6 | 1 | UniProt (Q9Y2R5) | Homo sapiens (human) | 28S ribosomal protein S17,mitochondrial,MRP-S17,S17mt |
| 23 | W (O) | 28S ribosomal protein S18b, mitochondrial | polymer | 193 | 22573.8 | 1 | Homo sapiens | ||
| 24 | X (P) | 28S ribosomal protein S18c, mitochondrial | polymer | 97 | 11188.2 | 1 | Homo sapiens | ||
| 25 | Y (Q) | 28S ribosomal protein S21, mitochondrial | polymer | 87 | 10764.7 | 1 | UniProt (P82921) | Homo sapiens (human) | S21mt,Mitochondrial small ribosomal subunit protein bS21m |
| 26 | Z (R) | Small ribosomal subunit protein mS22 | polymer | 295 | 34251.1 | 1 | UniProt (P82650) | Homo sapiens (human) | 28S ribosomal protein S22,mitochondrial,MRP-S22,S22mt |
| 27 | AA (S) | 28S ribosomal protein S23, mitochondrial | polymer | 135 | 15703.0 | 1 | Homo sapiens | ||
| 28 | BA (T) | Small ribosomal subunit protein mS25 | polymer | 168 | 19585.8 | 1 | UniProt (P82663) | Homo sapiens (human) | 28S ribosomal protein S25,mitochondrial,MRP-S25,S25mt |
| 29 | CA (U) | Small ribosomal subunit protein mS26 | polymer | 176 | 21183.1 | 1 | UniProt (Q9BYN8) | Homo sapiens (human) | 28S ribosomal protein S13,mitochondrial,MRP-S13,S13mt,28S ribosomal protein S26,MRP-S26,S26mt |
| 30 | DA (V) | Small ribosomal subunit protein mS27 | polymer | 379 | 43969.8 | 1 | UniProt (Q92552) | Homo sapiens (human) | 28S ribosomal protein S27,mitochondrial,MRP-S27,S27mt,Mitochondrial ribosomal protein S27 |
| 31 | EA (W) | Small ribosomal subunit protein bS1m | polymer | 100 | 11264.0 | 1 | UniProt (Q9Y2Q9) | Homo sapiens (human) | 28S ribosomal protein S28,mitochondrial,MRP-S28,S28mt,28S ribosomal protein S35,MRP-S35,S35mt |
| 32 | FA (X) | Small ribosomal subunit protein mS29 | polymer | 352 | 40421.3 | 1 | UniProt (P51398) | Homo sapiens (human) | 28S ribosomal protein S29,mitochondrial,MRP-S29,S29mt,Death-associated protein 3,DAP-3,Ionizing radiation resistance conferring protein |
| 33 | GA (Y) | 28S ribosomal protein S27, mitochondrial | polymer | 149 | 17631.8 | 1 | Homo sapiens | ||
| 34 | HA (Z) | Small ribosomal subunit protein mS33 | polymer | 100 | 11952.9 | 1 | UniProt (Q9Y291) | Homo sapiens (human) | 28S ribosomal protein S33,mitochondrial,MRP-S33,S33mt |
| 35 | AB, AC, AD, AE, BB... (A, X, 3, 7, B) | MAGNESIUM ION | non-polymer | 24.3 | 72 | Chemie (MG) | |||
| 36 | FC, GC, HC, IC, JA... (A, 7) | POTASSIUM ION | non-polymer | 39.1 | 20 | Chemie (K) | |||
| 37 | LA (7) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 38 | WD (O) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 39 | XD, YD (P, T) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 40 | ZD (X) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 41 | BE (X) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 42 | AF, BF, CE, CF, DE... (Q, R, 0, S, 1...) | water | water | 18.0 | 1399 | Chemie (HOH) |
Sequence modifications
Q: 1 - 87 (UniProt: P82921)
| PDB | External Database | Details |
|---|---|---|
| Arg 50 | Cys 50 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 34 |
| Total formula weight | 1065518.1 | |
| Non-Polymers* | Number of molecules | 98 |
| Total formula weight | 4422.5 | |
| All* | Total formula weight | 1069940.6 |
