9NAB
Cryo-EM structure of the alpha5beta1 integrin headpiece with OS2966 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin beta-1 | polymer | 498 | 55587.0 | 1 | UniProt (P05556) Pfam (PF17205) Pfam (PF00362) | Homo sapiens (human) | Fibronectin receptor subunit beta,Glycoprotein IIa,GPIIA,VLA-4 subunit beta |
| 2 | B (B) | Human Integrin alpha 5 | polymer | 694 | 74917.8 | 1 | Homo sapiens | ||
| 3 | C (D) | IgG heavy chain | polymer | 230 | 24866.8 | 1 | Mus musculus | ||
| 4 | D (C) | IgG light chain | polymer | 214 | 23208.8 | 1 | Mus musculus |
Sequence modifications
A: 21 - 465 (UniProt: P05556)
| PDB | External Database | Details |
|---|---|---|
| Gly 466 | - | expression tag |
| Gly 467 | - | expression tag |
| Leu 468 | - | expression tag |
| Glu 469 | - | expression tag |
| Asn 470 | - | expression tag |
| Leu 471 | - | expression tag |
| Tyr 472 | - | expression tag |
| Phe 473 | - | expression tag |
| Gln 474 | - | expression tag |
| Gly 475 | - | expression tag |
| Gly 476 | - | expression tag |
| Lys 477 | - | expression tag |
| Asn 478 | - | expression tag |
| Ala 479 | - | expression tag |
| Gln 480 | - | expression tag |
| Cys 481 | - | expression tag |
| Lys 482 | - | expression tag |
| Lys 483 | - | expression tag |
| Lys 484 | - | expression tag |
| Leu 485 | - | expression tag |
| Gln 486 | - | expression tag |
| Ala 487 | - | expression tag |
| Leu 488 | - | expression tag |
| Lys 489 | - | expression tag |
| Lys 490 | - | expression tag |
| Lys 491 | - | expression tag |
| Asn 492 | - | expression tag |
| Ala 493 | - | expression tag |
| Gln 494 | - | expression tag |
| Leu 495 | - | expression tag |
| Lys 496 | - | expression tag |
| Trp 497 | - | expression tag |
| Lys 498 | - | expression tag |
| Leu 499 | - | expression tag |
| Gln 500 | - | expression tag |
| Ala 501 | - | expression tag |
| Leu 502 | - | expression tag |
| Lys 503 | - | expression tag |
| Lys 504 | - | expression tag |
| Lys 505 | - | expression tag |
| Leu 506 | - | expression tag |
| Ala 507 | - | expression tag |
| Gln 508 | - | expression tag |
| Gly 509 | - | expression tag |
| Gly 510 | - | expression tag |
| His 511 | - | expression tag |
| His 512 | - | expression tag |
| His 513 | - | expression tag |
| His 514 | - | expression tag |
| His 515 | - | expression tag |
| His 516 | - | expression tag |
| His 517 | - | expression tag |
| His 518 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 178580.4 | |
| All* | Total formula weight | 178580.4 |
