9N1Z

Structure of C3d Bound to a Fragment of FHR-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Complement C3dg fragment	polymer	297	33143.9	2	UniProt (P01024) Pfam (PF07678)	Homo sapiens (human)
2	B, D (B, D)	Complement factor H-related protein 2	polymer	131	14662.5	2	UniProt (P36980) Pfam (PF00084)	Homo sapiens (human)	FHR-2,DDESK59,H factor-like 3,H factor-like protein 2
3	E, F, G, H (A, B, D)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
4	I, J, K, L (A, B, C, D)	water	water		18.0	363	Chemie (HOH)

Sequence modifications

A, C: 996 - 1287 (UniProt: P01024)

PDB	External Database	Details
Gly 991	-	expression tag
Ser 992	-	expression tag
Arg 993	-	expression tag
Ser 994	-	expression tag
Thr 995	-	expression tag
Ala 1010	Cys 1010	engineered mutation

B, D: 145 - 270 (UniProt: P36980)

PDB	External Database	Details
Gly 140	-	expression tag
Ser 141	-	expression tag
Thr 142	-	expression tag
Gly 143	-	expression tag
Ser 144	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	95612.8
Non-Polymers*	Number of molecules	4
	Total formula weight	384.3
All*	Total formula weight	95997.0

*Water molecules are not included.