9MJ5
Catalytic domain of human DNA polymerase alpha in complex with DNA and RPA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Replication protein A 14 kDa subunit | polymer | 121 | 13583.7 | 1 | UniProt (P35244) Pfam (PF08661) | Homo sapiens (human) | RP-A p14,Replication factor A protein 3,RF-A protein 3 |
| 2 | B (B) | Replication protein A 32 kDa subunit | polymer | 236 | 25931.4 | 1 | UniProt (P15927) Pfam (PF08784) | Homo sapiens (human) | RP-A p32,Replication factor A protein 2,RF-A protein 2,Replication protein A 34 kDa subunit,RP-A p34 |
| 3 | C (C) | Replication protein A 70 kDa DNA-binding subunit | polymer | 179 | 21031.7 | 1 | UniProt (P27694) Pfam (PF08646) | Homo sapiens (human) | RP-A p70,Replication factor A protein 1,RF-A protein 1,Single-stranded DNA-binding protein |
| 4 | D (P) | RNA-DNA primer (11-mer) | polymer | 11 | 3505.2 | 1 | Homo sapiens | ||
| 5 | E (S) | DNA polymerase alpha catalytic subunit | polymer | 910 | 103957.1 | 1 | UniProt (P09884) Pfam (PF03104) Pfam (PF00136) | Homo sapiens (human) | DNA polymerase alpha catalytic subunit p180 |
| 6 | F (T) | DNA template (35-mer) | polymer | 35 | 10765.0 | 1 | Homo sapiens | ||
| 7 | G (C) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 8 | H (S) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 9 | I (S) | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE | non-polymer | 467.2 | 1 | Chemie (DCP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 178774.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 556.9 | |
| All* | Total formula weight | 179330.9 |
