9M1Z

Crystal Structure of MAP2K6 complexed with 5Z-7-oxozeaenol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (D, A, B, C)	Dual specificity mitogen-activated protein kinase kinase 6	polymer	340	38369.2	4	UniProt (P52564)	Homo sapiens (human)	MAP kinase kinase 6,MAPKK 6,MAPK/ERK kinase 6,MEK 6,Stress-activated protein kinase kinase 3,SAPK kinase 3,SAPKK-3,SAPKK3
2	E, F, G, H (D, A, B, C)	(3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione	non-polymer		362.4	4	Chemie (1FM)
3	I, J, K, L (D, A, B, C)	water	water		18.0	81	Chemie (HOH)

Sequence modifications

D, A, B, C: 1 - 334 (UniProt: P52564)

PDB	External Database	Details
His 335	-	expression tag
His 336	-	expression tag
His 337	-	expression tag
His 338	-	expression tag
His 339	-	expression tag
His 340	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	153476.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1449.5
All*	Total formula weight	154926.3

*Water molecules are not included.