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9KFU

Human FGFR3 in complex with inhibitor F1

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Fibroblast growth factor receptor 3polymer30934734.11UniProt (P22607)
Pfam (PF07714)
Homo sapiens (human)FGFR-3
2B
(A)
(7~{S})-2-azanyl-7-(4-fluorophenyl)-6,7-dihydro-4~{H}-[1,3]thiazolo[4,5-b]pyridin-5-onenon-polymer263.31Chemie (A1L5T)
3C, D, E, F
(A)
SULFATE IONnon-polymer96.14Chemie (SO4)
4G
(A)
COBALT (II) IONnon-polymer58.91Chemie (CO)
5H
(A)
waterwater18.0179Chemie (HOH)
Sequence modifications
A: 448 - 756 (UniProt: P22607)
PDBExternal DatabaseDetails
Ala 482Cys 482conflict
Gln 587Glu 587conflict
Asn 649Lys 649conflict
Thr 650Lys 650conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34734.1
Non-Polymers*Number of molecules6
Total formula weight706.5
All*Total formula weight35440.5
*Water molecules are not included.

244349

PDB entries from 2025-11-05

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