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9K0I

Crystal structure of FGFR4 kinase domain with 32a

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Fibroblast growth factor receptor 4polymer31134663.01UniProt (P22455)
Pfam (PF07714)
Homo sapiens (human)FGFR-4
2B
(A)
(2~{S})-~{N}-[2-[[5-[(1~{R})-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1~{H}-indazol-3-yl]amino]-3-fluoranyl-5-(4-morpholin-4-ylpiperidin-1-yl)phenyl]-2-cyano-3-cyclopropyl-propanamidenon-polymer721.71Chemie (A1EEW)
3C, D, E, F, G...
(A)
SULFATE IONnon-polymer96.17Chemie (SO4)
4J
(A)
waterwater18.0157Chemie (HOH)
Sequence modifications
A: 445 - 753 (UniProt: P22455)
PDBExternal DatabaseDetails
Gly 443-expression tag
Pro 444-expression tag
Ala 477Cys 477conflict
Glu 664Arg 664conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34663.0
Non-Polymers*Number of molecules8
Total formula weight1394.1
All*Total formula weight36057.1
*Water molecules are not included.

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PDB entries from 2025-10-29

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