9IXR

Crystal structure of OXA-10 variant A124T in the complex with ceftazidime

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-lactamase OXA-10	polymer	248	27823.7	2	UniProt (P14489) UniProt (by SIFTS) (Q6QJ55)	Pseudomonas aeruginosa	Beta-lactamase PSE-2
2	C, D (A, B)	1-({(2R)-2-[(1R)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-oxoethyl]-4-carboxy-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium	non-polymer		549.6	2	Chemie (CTJ)
3	E, F (A, B)	water	water		18.0	228	Chemie (HOH)

Sequence modifications

A, B: 21 - 265 (UniProt: P14489)

PDB	External Database	Details
Gly 18	-	expression tag
His 19	-	expression tag
Met 20	-	expression tag
Thr 124	Ala 124	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55647.3
Non-Polymers*	Number of molecules	2
	Total formula weight	1099.2
All*	Total formula weight	56746.5

*Water molecules are not included.