9IXR

Crystal structure of OXA-10 variant A124T in the complex with ceftazidime

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008658	molecular_function	penicillin binding
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0046677	biological_process	response to antibiotic
A	0071555	biological_process	cell wall organization
B	0005886	cellular_component	plasma membrane
B	0008658	molecular_function	penicillin binding
B	0008800	molecular_function	beta-lactamase activity
B	0016787	molecular_function	hydrolase activity
B	0017001	biological_process	antibiotic catabolic process
B	0046677	biological_process	response to antibiotic
B	0071555	biological_process	cell wall organization

Functional Information from PROSITE/UniProt

site_id	PS00337
Number of Residues	11
Details	BETA_LACTAMASE_D Beta-lactamase class-D active site. PaSTFKIPnAI

Chain	Residue	Details
A	PRO65-ILE75

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Acyl-ester intermediate => ECO:0000269|PubMed:11724923, ECO:0000269|PubMed:19860471, ECO:0007744|PDB:1K54, ECO:0007744|PDB:2WGI

Chain	Residue	Details
A	SER67
B	SER67

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site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:19860471, ECO:0007744|PDB:2WGI

Chain	Residue	Details
A	SER115
A	THR206
A	PHE208
A	ARG250
B	SER115
B	THR206
B	PHE208
B	ARG250

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: N6-carboxylysine => ECO:0000269|PubMed:11188693, ECO:0000269|PubMed:11724923, ECO:0000269|PubMed:19860471, ECO:0007744|PDB:1E4D, ECO:0007744|PDB:1K4E, ECO:0007744|PDB:1K4F, ECO:0007744|PDB:1K54, ECO:0007744|PDB:1K55, ECO:0007744|PDB:1K56, ECO:0007744|PDB:1K57, ECO:0007744|PDB:1K6S, ECO:0007744|PDB:2RL3

Chain	Residue	Details
A	LYS70
B	LYS70

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