9INH
Cryo-EM structure of human XPR1 in complex with InsP6 in outward-facing state (SPX visible)-in the presence of KIDINS220-1-432 and 10 mM KH2PO4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, D) | Solute carrier family 53 member 1 | polymer | 704 | 82674.0 | 2 | UniProt (Q9UBH6) Pfam (PF03105) Pfam (PF03124) | Homo sapiens (human) | Phosphate exporter SLC53A1,Protein SYG1 homolog,Xenotropic and polytropic murine leukemia virus receptor X3,X-receptor,Xenotropic and polytropic retrovirus receptor 1 |
| 2 | C, T (A, D) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 2 | Chemie (IHP) | |||
| 3 | AA, CA, D, DA, EA... (D, A) | CHOLESTEROL | non-polymer | 386.7 | 12 | Chemie (CLR) | |||
| 4 | BA, E, GA, J, S... (D, A) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 6 | Chemie (3PE) | |||
| 5 | HA, K (D, A) | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) | |||
| 6 | JA, M (D, A) | ARACHIDONIC ACID | non-polymer | 304.5 | 2 | Chemie (ACD) | |||
| 7 | N, O, P, Q, R... (A, D) | PHOSPHATE ION | non-polymer | 95.0 | 10 | Chemie (PO4) |
Sequence modifications
A, D: 1 - 696 (UniProt: Q9UBH6)
| PDB | External Database | Details |
|---|---|---|
| Ser 697 | - | expression tag |
| Arg 698 | - | expression tag |
| Glu 699 | - | expression tag |
| Asn 700 | - | expression tag |
| Leu 701 | - | expression tag |
| Tyr 702 | - | expression tag |
| Phe 703 | - | expression tag |
| Gln 704 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 165348.0 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 12519.8 | |
| All* | Total formula weight | 177867.8 |
