9IK1
Cryo-EM structure of the human P2X3 receptor-compound 26a complex
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | P2X purinoceptor 3 | polymer | 359 | 40373.5 | 3 | UniProt (P56373) Pfam (PF00864) | Homo sapiens (human) | P2X3,ATP receptor,Purinergic receptor |
| 2 | D, J, P (A, B, C) | 4-[2-cyclopropyl-7-[[(1~{R})-1-naphthalen-2-ylethyl]amino]-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperazine-1-carboxamide | non-polymer | 456.5 | 3 | Chemie (A1L2M) | |||
| 3 | E, K, Q (A, B, C) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) | |||
| 4 | F, G, H, L, M... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 5 | I, O, U (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) |
Sequence modifications
A, B, C: 6 - 364 (UniProt: P56373)
| PDB | External Database | Details |
|---|---|---|
| Pro 13 | Thr 13 | conflict |
| Val 15 | Ser 15 | conflict |
| Ile 16 | Val 16 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 121120.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 4955.0 | |
| All* | Total formula weight | 126075.5 |
