9HYT
Crystal structure of the GFRaL receptor in complex with an inhibitory cyclic peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | GDNF family receptor alpha-like | polymer | 245 | 27665.7 | 3 | UniProt (Q6UXV0) Pfam (PF02351) | Homo sapiens (human) | |
| 2 | D, E, F (D, E, F) | Inhibitory cyclic peptide | polymer | 17 | 1792.1 | 3 | synthetic construct | ||
| 3 | G, H, J, K, L... (A, B, C) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 4 | I (B) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 5 | O, P, Q (D, E, F) | 1,1',1''-(1,3,5-triazinane-1,3,5-triyl)tripropan-1-one | non-polymer | 255.3 | 3 | Chemie (29N) | |||
| 6 | R, S, T, U, V... (A, B, C, D, E...) | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A, B, C: 115 - 351 (UniProt: Q6UXV0)
| PDB | External Database | Details |
|---|---|---|
| His 107 | - | expression tag |
| His 108 | - | expression tag |
| His 109 | - | expression tag |
| His 110 | - | expression tag |
| His 111 | - | expression tag |
| His 112 | - | expression tag |
| Gly 113 | - | expression tag |
| Gly 114 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 88373.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1498.4 | |
| All* | Total formula weight | 89871.8 |
