9HJS
Crystal structure of human geranylgeranyl diphosphate synthase mutant R235C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Geranylgeranyl pyrophosphate synthase | polymer | 307 | 35382.2 | 6 | UniProt (O95749) | Homo sapiens (human) | GGPP synthase,GGPPSase,(2E,6E)-farnesyl diphosphate synthase,Dimethylallyltranstransferase,Farnesyl diphosphate synthase,Farnesyltranstransferase,Geranylgeranyl diphosphate synthase,Geranyltranstransferase |
| 2 | G, J, M, P, S... (A, B, C, D, E...) | GERANYLGERANYL DIPHOSPHATE | non-polymer | 450.4 | 6 | Chemie (GRG) | |||
| 3 | H, I, K, L, N... (A, B, C, D, E...) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
| 4 | AA, BA, CA, DA, Y... (C, D, E, F, A...) | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 300 (UniProt: O95749)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gln 109 | Pro 109 | variant |
| Cys 235 | Arg 235 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 212293.4 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2994.3 | |
| All* | Total formula weight | 215287.7 |
