9GTK
KRAS in complex with DARPin 784_F5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D (A, C, D) | Isoform 2B of GTPase KRas | polymer | 195 | 22225.3 | 3 | UniProt (P01116) | Homo sapiens (human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B, E, F (B, H, I) | DARPin 784_F5 | polymer | 170 | 18170.4 | 3 | synthetic construct | ||
| 3 | AA, DA, EA, FA, G... (B, C, A, D, I) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 30 | Chemie (EDO) | |||
| 4 | MA, R, S, SA, VA... (C, A, D, H, I) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 5 | NA, T, TA (C, A, D) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 3 | Chemie (GNP) | |||
| 6 | BA (B) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 7 | CA, OA, UA, WA (B, C, D, H) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 4 | Chemie (PGE) | |||
| 8 | PA (C) | S,R MESO-TARTARIC ACID | non-polymer | 150.1 | 1 | Chemie (SRT) | |||
| 9 | AB, BB, CB, DB, EB... (B, C, D, H, I...) | water | water | 18.0 | 564 | Chemie (HOH) |
Sequence modifications
A, C, D: 1 - 186 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly 187 | - | expression tag |
| Ser 188 | - | expression tag |
| Ala 189 | - | expression tag |
| Glu 190 | - | expression tag |
| Asn 191 | - | expression tag |
| Leu 192 | - | expression tag |
| Tyr 193 | - | expression tag |
| Phe 194 | - | expression tag |
| Gln 195 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 121187.2 | |
| Non-Polymers* | Number of molecules | 45 |
| Total formula weight | 4563.5 | |
| All* | Total formula weight | 125750.8 |
