9GSU

Structure of PP1-Neurabin bound to 4E-BP1.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, D)	Serine/threonine-protein phosphatase	polymer	340	38167.5	2	UniProt (A0A8C3UBZ3) Pfam (PF16891) Pfam (PF00149)	Homo sapiens (human)
2	B, D (C, E)	Neurabin-1	polymer	176	19405.4	2	UniProt (Q9ULJ8) Pfam (PF17817) Pfam (PF00595)	Homo sapiens (human)	Neurabin-I,Neural tissue-specific F-actin-binding protein I,Protein phosphatase 1 regulatory subunit 9A
3	E, F, G, H (A, D)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)
4	I, J (A, D)	water	water		18.0	20	Chemie (HOH)

Sequence modifications

A, D: 7 - 1081 (UniProt: A0A8C3UBZ3)

PDB	External Database	Details
Gly 2	-	expression tag
His 3	-	expression tag
Met 4	-	expression tag
Gly 5	-	expression tag
Ser 6	-	expression tag
Gly 14	Ser 14	conflict
Ser 1082	-	expression tag
Gly 1083	-	expression tag
Ser 1084	-	expression tag
Gly 1085	-	expression tag
Ser 1086	-	expression tag
Gly 1087	-	expression tag
Ser 1088	-	expression tag
Gly 1089	-	expression tag
Ser 1090	-	expression tag
Gly 1091	-	expression tag
Ser 1092	-	expression tag
Pro 1093	-	expression tag
Val 1094	-	expression tag
Thr 1095	-	expression tag
Lys 1096	-	expression tag
Thr 1097	-	expression tag
Pro 1098	-	expression tag
Pro 1099	-	expression tag
Arg 1100	-	expression tag
Asp 1101	-	expression tag
Leu 1102	-	expression tag
Pro 1103	-	expression tag
Thr 1104	-	expression tag
Ile 1105	-	expression tag
Pro 1106	-	expression tag
Gly 1107	-	expression tag
Val 1108	-	expression tag
Thr 1109	-	expression tag
Ser 1110	-	expression tag
Gly 1111	-	expression tag
Ser 1112	-	expression tag
Gln 1113	-	expression tag
Phe 1114	-	expression tag
Glu 1115	-	expression tag
Met 1116	-	expression tag
Asp 1117	-	expression tag
Ile 1118	-	expression tag

C, E: 423 - 593 (UniProt: Q9ULJ8)

PDB	External Database	Details
Gly 418	-	expression tag
Pro 419	-	expression tag
Leu 420	-	expression tag
Gly 421	-	expression tag
Ser 422	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	115145.8
Non-Polymers*	Number of molecules	4
	Total formula weight	219.8
All*	Total formula weight	115365.6

*Water molecules are not included.