9FZR
Wild-type EGFR in covalent complex with Poziotinib analogue
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 329 | 37458.3 | 1 | UniProt (P00533) Pfam (PF07714) | Homo sapiens (human) | Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1 |
| 2 | B (A) | 1-[(3~{S})-3-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-methoxy-quinazolin-6-yl]oxypyrrolidin-1-yl]propan-1-one | non-polymer | 444.9 | 1 | Chemie (A1IHC) | |||
| 3 | C (A) | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence modifications
A: 696 - 1022 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Gly 694 | - | expression tag |
| Pro 695 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37458.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 444.9 | |
| All* | Total formula weight | 37903.2 |
