9ESA
Aurora-C with SER mutation in complex with INCENP peptide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | Aurora kinase C | polymer | 303 | 34988.3 | 2 | UniProt (Q9UQB9) Pfam (PF00069) | Homo sapiens (human) | Aurora 3,Aurora/IPL1-related kinase 3,ARK-3,Aurora-related kinase 3,Aurora/IPL1/Eg2 protein 2,Serine/threonine-protein kinase 13,Serine/threonine-protein kinase aurora-C |
| 2 | C, D (CCC, DDD) | Inner centromere protein | polymer | 58 | 6857.9 | 2 | UniProt (Q9NQS7) Pfam (PF03941) | Homo sapiens (human) | |
| 3 | E (BBB) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | F, G, H, I (AAA, BBB, CCC, DDD) | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 13 - 309 (UniProt: Q9UQB9)
| PDB | External Database | Details |
|---|---|---|
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| Ala 195 | Arg 195 | engineered mutation |
| Ala 196 | Arg 196 | engineered mutation |
| Ala 197 | Lys 197 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 83692.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 62.1 | |
| All* | Total formula weight | 83754.6 |
