9ESA

Aurora-C with SER mutation in complex with INCENP peptide

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0000166	molecular_function	nucleotide binding
AAA	0000775	cellular_component	chromosome, centromeric region
AAA	0000776	cellular_component	kinetochore
AAA	0000793	cellular_component	condensed chromosome
AAA	0000922	cellular_component	spindle pole
AAA	0004672	molecular_function	protein kinase activity
AAA	0004674	molecular_function	protein serine/threonine kinase activity
AAA	0004712	molecular_function	protein serine/threonine/tyrosine kinase activity
AAA	0005515	molecular_function	protein binding
AAA	0005524	molecular_function	ATP binding
AAA	0005634	cellular_component	nucleus
AAA	0005694	cellular_component	chromosome
AAA	0005813	cellular_component	centrosome
AAA	0005819	cellular_component	spindle
AAA	0005876	cellular_component	spindle microtubule
AAA	0006468	biological_process	protein phosphorylation
AAA	0007052	biological_process	mitotic spindle organization
AAA	0008608	biological_process	attachment of spindle microtubules to kinetochore
AAA	0016301	molecular_function	kinase activity
AAA	0016570	biological_process	obsolete histone modification
AAA	0016740	molecular_function	transferase activity
AAA	0030496	cellular_component	midbody
AAA	0032133	cellular_component	chromosome passenger complex
AAA	0032465	biological_process	regulation of cytokinesis
AAA	0032467	biological_process	positive regulation of cytokinesis
AAA	0051233	cellular_component	spindle midzone
AAA	0051256	biological_process	mitotic spindle midzone assembly
AAA	0051301	biological_process	cell division
AAA	0051321	biological_process	meiotic cell cycle
AAA	0106310	molecular_function	protein serine kinase activity
BBB	0000166	molecular_function	nucleotide binding
BBB	0000775	cellular_component	chromosome, centromeric region
BBB	0000776	cellular_component	kinetochore
BBB	0000793	cellular_component	condensed chromosome
BBB	0000922	cellular_component	spindle pole
BBB	0004672	molecular_function	protein kinase activity
BBB	0004674	molecular_function	protein serine/threonine kinase activity
BBB	0004712	molecular_function	protein serine/threonine/tyrosine kinase activity
BBB	0005515	molecular_function	protein binding
BBB	0005524	molecular_function	ATP binding
BBB	0005634	cellular_component	nucleus
BBB	0005694	cellular_component	chromosome
BBB	0005813	cellular_component	centrosome
BBB	0005819	cellular_component	spindle
BBB	0005876	cellular_component	spindle microtubule
BBB	0006468	biological_process	protein phosphorylation
BBB	0007052	biological_process	mitotic spindle organization
BBB	0008608	biological_process	attachment of spindle microtubules to kinetochore
BBB	0016301	molecular_function	kinase activity
BBB	0016570	biological_process	obsolete histone modification
BBB	0016740	molecular_function	transferase activity
BBB	0030496	cellular_component	midbody
BBB	0032133	cellular_component	chromosome passenger complex
BBB	0032465	biological_process	regulation of cytokinesis
BBB	0032467	biological_process	positive regulation of cytokinesis
BBB	0051233	cellular_component	spindle midzone
BBB	0051256	biological_process	mitotic spindle midzone assembly
BBB	0051301	biological_process	cell division
BBB	0051321	biological_process	meiotic cell cycle
BBB	0106310	molecular_function	protein serine kinase activity

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	24
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGKGKFGNVYlArlkeshfi..........VALK

Chain	Residue	Details
AAA	LEU49-LYS72

---

site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ViHrDIKpeNLLL

Chain	Residue	Details
AAA	VAL162-LEU174

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	500
Details	Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine; by PKA","evidences":[{"source":"UniProtKB","id":"O88445","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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