9EO4
Outward-open structure of human dopamine transporter bound to cocaine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Sodium-dependent dopamine transporter | polymer | 660 | 72209.3 | 1 | UniProt (Q01959) Pfam (PF00209) In PDB | Homo sapiens (human) | DA transporter,DAT,Solute carrier family 6 member 3 |
2 | B | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) | |||
3 | B | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) | |||
4 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
5 | B | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
6 | B | COCAINE | non-polymer | 303.4 | 1 | Chemie (COC) | |||
7 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
B: 1 - 620 (UniProt: Q01959)
PDB | External Database | Details |
---|---|---|
Gly 621 | - | expression tag |
Gly 622 | - | expression tag |
Gly 623 | - | expression tag |
Ser 624 | - | expression tag |
Gly 625 | - | expression tag |
Gly 626 | - | expression tag |
Gly 627 | - | expression tag |
Ser 628 | - | expression tag |
Gly 629 | - | expression tag |
Gly 630 | - | expression tag |
Ser 631 | - | expression tag |
Ala 632 | - | expression tag |
Trp 633 | - | expression tag |
Ser 634 | - | expression tag |
His 635 | - | expression tag |
Pro 636 | - | expression tag |
Gln 637 | - | expression tag |
Phe 638 | - | expression tag |
Glu 639 | - | expression tag |
Lys 640 | - | expression tag |
Gly 641 | - | expression tag |
Gly 642 | - | expression tag |
Gly 643 | - | expression tag |
Ser 644 | - | expression tag |
Gly 645 | - | expression tag |
Gly 646 | - | expression tag |
Gly 647 | - | expression tag |
Ser 648 | - | expression tag |
Gly 649 | - | expression tag |
Gly 650 | - | expression tag |
Ser 651 | - | expression tag |
Ala 652 | - | expression tag |
Trp 653 | - | expression tag |
Ser 654 | - | expression tag |
His 655 | - | expression tag |
Pro 656 | - | expression tag |
Gln 657 | - | expression tag |
Phe 658 | - | expression tag |
Glu 659 | - | expression tag |
Lys 660 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 72209.3 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 2008.5 | |
All* | Total formula weight | 74217.8 |