9EO4
Outward-open structure of human dopamine transporter bound to cocaine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Sodium-dependent dopamine transporter | polymer | 660 | 72209.3 | 1 | UniProt (Q01959) Pfam (PF00209) | Homo sapiens (human) | DA transporter,DAT,Solute carrier family 6 member 3 |
| 2 | B, D, E (B) | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) | |||
| 3 | C (B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) | |||
| 4 | F (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | G (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | H (B) | COCAINE | non-polymer | 303.4 | 1 | Chemie (COC) | |||
| 7 | I (B) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
B: 1 - 620 (UniProt: Q01959)
| PDB | External Database | Details |
|---|---|---|
| Gly 621 | - | expression tag |
| Gly 622 | - | expression tag |
| Gly 623 | - | expression tag |
| Ser 624 | - | expression tag |
| Gly 625 | - | expression tag |
| Gly 626 | - | expression tag |
| Gly 627 | - | expression tag |
| Ser 628 | - | expression tag |
| Gly 629 | - | expression tag |
| Gly 630 | - | expression tag |
| Ser 631 | - | expression tag |
| Ala 632 | - | expression tag |
| Trp 633 | - | expression tag |
| Ser 634 | - | expression tag |
| His 635 | - | expression tag |
| Pro 636 | - | expression tag |
| Gln 637 | - | expression tag |
| Phe 638 | - | expression tag |
| Glu 639 | - | expression tag |
| Lys 640 | - | expression tag |
| Gly 641 | - | expression tag |
| Gly 642 | - | expression tag |
| Gly 643 | - | expression tag |
| Ser 644 | - | expression tag |
| Gly 645 | - | expression tag |
| Gly 646 | - | expression tag |
| Gly 647 | - | expression tag |
| Ser 648 | - | expression tag |
| Gly 649 | - | expression tag |
| Gly 650 | - | expression tag |
| Ser 651 | - | expression tag |
| Ala 652 | - | expression tag |
| Trp 653 | - | expression tag |
| Ser 654 | - | expression tag |
| His 655 | - | expression tag |
| Pro 656 | - | expression tag |
| Gln 657 | - | expression tag |
| Phe 658 | - | expression tag |
| Glu 659 | - | expression tag |
| Lys 660 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 72209.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2008.5 | |
| All* | Total formula weight | 74217.8 |
