9EK5
TRIM21 PrySpry domain bound to an enhanced PRLX-93936 analog
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase TRIM21 | polymer | 181 | 20506.0 | 1 | UniProt (P19474) | Homo sapiens (human) | 52 kDa Ro protein,52 kDa ribonucleoprotein autoantigen Ro/SS-A,RING finger protein 81,Ro(SS-A),Sjoegren syndrome type A antigen,SS-A,Tripartite motif-containing protein 21 |
| 2 | B (A) | (3P)-3-(4-chloro-2-ethoxyphenyl)-6-fluoro-2-[(piperazin-1-yl)methyl]quinazolin-4(3H)-one | non-polymer | 416.9 | 1 | Chemie (A1BLD) | |||
| 3 | C (A) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A: 288 - 465 (UniProt: P19474)
| PDB | External Database | Details |
|---|---|---|
| Ser 285 | - | expression tag |
| Asn 286 | - | expression tag |
| Ala 287 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20506.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 416.9 | |
| All* | Total formula weight | 20922.9 |
