9DOD
Crystal structure of PRMT5:MEP50 in complex with PRT543
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein arginine N-methyltransferase 5 | polymer | 636 | 72635.5 | 1 | UniProt (O14744) Pfam (PF17285) Pfam (PF05185) Pfam (PF17286) | Homo sapiens (human) | PRMT5,72 kDa ICln-binding protein,Histone-arginine N-methyltransferase PRMT5,Jak-binding protein 1,Shk1 kinase-binding protein 1 homolog,SKB1 homolog,SKB1Hs |
| 2 | B (B) | Methylosome protein WDR77 | polymer | 341 | 36626.1 | 1 | UniProt (Q9BQA1) Pfam (PF00400) | Homo sapiens (human) | Androgen receptor cofactor p44,Methylosome protein 50,MEP-50,WD repeat-containing protein 77,p44/Mep50 |
| 3 | C (A) | 7-[(3xi,5R)-5-C-(3,4-dichlorophenyl)-3-C-methyl-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine | non-polymer | 425.3 | 1 | Chemie (A1A79) | |||
| 4 | D, E, F, G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 109261.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 673.5 | |
| All* | Total formula weight | 109935.0 |
