9DMH
Human muscle nAChR ACh-bound state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Acetylcholine receptor subunit alpha | polymer | 457 | 51889.3 | 2 | UniProt (P02708) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 2 | C (E) | Acetylcholine receptor subunit beta | polymer | 503 | 57000.4 | 1 | UniProt (P11230) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 3 | D (D) | Acetylcholine receptor subunit delta | polymer | 517 | 58955.8 | 1 | UniProt (Q07001) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 4 | E (B) | Acetylcholine receptor subunit epsilon | polymer | 493 | 54743.8 | 1 | UniProt (Q04844) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | |
| 5 | F (F) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 6 | G, J (G, J) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 7 | H (H) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 8 | I (I) | beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G42769XG) | |||
| 9 | K (K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 10 | L, M (A, C) | ACETYLCHOLINE | non-polymer | 146.2 | 2 | Chemie (ACH) | |||
| 11 | N, O, P (E, D, B) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 3 | Chemie (POV) | |||
| 12 | Q, R (A, C) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
E: -22 - 478 (UniProt: P11230)
| PDB | External Database | Details |
|---|---|---|
| Ser 479 | - | expression tag |
| Arg 480 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 274478.5 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 4654.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2572.6 | |
| All* | Total formula weight | 281705.4 |
