9DMH
Human muscle nAChR ACh-bound state
Functional Information from PROSITE/UniProt
| site_id | PS00236 |
| Number of Residues | 15 |
| Details | NEUROTR_ION_CHANNEL Neurotransmitter-gated ion-channels signature. CeIiVthFPfDeqnC |
| Chain | Residue | Details |
| A | CYS128-CYS142 | |
| D | CYS130-CYS144 | |
| E | CYS128-CYS142 | |
| B | CYS128-CYS142 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 244 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| B | LYS1-LYS219 | |
| B | GLN272-ARG286 | |
| B | ARG461-PRO473 | |
| C | SER1-LEU212 | |
| C | SER266-LYS276 | |
| C | ARG429-GLY437 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 86 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| B | PRO220-LEU244 | |
| B | CYS253-ALA271 | |
| B | PHE287-VAL308 | |
| B | ILE437-ASN460 | |
| C | TYR213-PHE233 | |
| C | LEU245-PRO265 | |
| C | TYR277-ASN297 | |
| C | HIS408-GLY428 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 134 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| B | PRO245-LYS252 | |
| B | SER309-ASN436 | |
| C | TYR234-THR244 | |
| C | THR298-ASP407 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN66 | |
| B | ASN141 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| D | ASN76 | |
| D | ASN143 |
