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9CYC

SARS-CoV-2 PLpro in complex with inhibitor WEHI-P2

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Papain-like proteasepolymer31835927.72UniProt (P0DTC1)
Pfam (PF08715)
Severe acute respiratory syndrome coronavirus 2Non-structural protein 3, nsp3, PL2-PRO, Papain-like proteinase, PL-PRO
2C, H
(A, B)
(E)-1-[(3R)-1-cyclopentylpiperidin-3-yl]-N-methoxy-1-(6-methoxynaphthalen-2-yl)methaniminenon-polymer366.52Chemie (A1A0S)
3D, I
(A, B)
ACETIC ACIDnon-polymer60.12Chemie (ACY)
4E, F, G, J
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
5K, L
(A, B)
waterwater18.0188Chemie (HOH)
Sequence modifications
A, B: 1 - 315 (UniProt: P0DTC1)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
Ser 111Cys 1674engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight71855.4
Non-Polymers*Number of molecules8
Total formula weight1221.5
All*Total formula weight73076.9
*Water molecules are not included.

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PDB entries from 2025-07-16

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