9CRA

CryoEM Structure of the C-terminally truncated form of human NAD Kinase bound to NAD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	NAD kinase	polymer	373	41069.9	4	UniProt (O95544) Pfam (PF01513) Pfam (PF20143)	Homo sapiens (human)	Poly(P)/ATP NAD kinase
2	E, F, G, H (A, B, C, D)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	4	Chemie (NAD)

Sequence modifications

A, B, C, D: 91 - 437 (UniProt: O95544)

PDB	External Database	Details
Met 67	-	initiating methionine
Pro 68	-	expression tag
Ser 69	-	expression tag
Pro 70	-	expression tag
Val 71	-	expression tag
Thr 72	-	expression tag
Thr 73	-	expression tag
Phe 74	-	expression tag
Gly 75	-	expression tag
Pro 76	-	expression tag
Lys 77	-	expression tag
Ala 78	-	expression tag
Thr 79	-	expression tag
Val 80	-	expression tag
Glu 89	-	expression tag
Thr 90	-	expression tag
Val 96	Gln 96	conflict
Thr 162	Cys 162	conflict
Thr 402	Cys 402	conflict
Leu 438	-	expression tag
Gly 439	-	expression tag
Leu 440	-	expression tag
Glu 441	-	expression tag
His 442	-	expression tag
His 443	-	expression tag
His 444	-	expression tag
His 445	-	expression tag
His 446	-	expression tag
His 447	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	164279.6
Non-Polymers*	Number of molecules	4
	Total formula weight	2653.7
All*	Total formula weight	166933.3

*Water molecules are not included.