9BZ0
Structure of an STK19-containing TC-NER complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-directed RNA polymerase subunit | polymer | 1984 | 218889.5 | 1 | UniProt (A0A7M4DUC2) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) | Sus scrofa (pig) | |
| 2 | B (B) | DNA-directed RNA polymerase subunit beta | polymer | 1251 | 142426.1 | 1 | UniProt (A0A4X1TVZ5) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) UniProt (by SIFTS) (A0A0B8RVL1) | Sus scrofa (pig) | |
| 3 | C (C) | DNA-directed RNA polymerase II subunit RPB3 | polymer | 275 | 31439.1 | 1 | UniProt (A0A481DF93) Pfam (PF01193) Pfam (PF01000) UniProt (by SIFTS) (I3LCH3) | Sus scrofa (pig) | |
| 4 | D (D) | RNA polymerase Rpb4/RPC9 core domain-containing protein | polymer | 142 | 16331.3 | 1 | UniProt (A0A8D0KES4) | Sus scrofa (pig) | |
| 5 | E (E) | DNA-directed RNA polymerase II subunit E | polymer | 210 | 24644.3 | 1 | UniProt (A0A4X1VTX4) Pfam (PF03871) Pfam (PF01191) UniProt (by SIFTS) (I3LSI7) | Sus scrofa (pig) | RPB5 |
| 6 | F (F) | DNA-directed RNA polymerases I, II, and III subunit RPABC2 | polymer | 127 | 14477.0 | 1 | UniProt (A0A4X1VEK9) Pfam (PF01192) | Sus scrofa (pig) | DNA-directed RNA polymerase II subunit F,RPB6 homolog |
| 7 | G (G) | DNA-directed RNA polymerase II subunit RPB7 | polymer | 172 | 19314.3 | 1 | UniProt (A0A4X1VKG7) Pfam (PF03876) Pfam (PF00575) | Sus scrofa (pig) | |
| 8 | H (H) | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 150 | 17162.3 | 1 | UniProt (A0A8D1AQR7) Pfam (PF03870) | Sus scrofa (pig) | |
| 9 | I (I) | DNA-directed RNA polymerase II subunit RPB9 | polymer | 125 | 14541.2 | 1 | UniProt (P60899) Pfam (PF02150) Pfam (PF01096) | Sus scrofa (pig) | RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5 |
| 10 | J (J) | DNA-directed RNA polymerases I, II, and III subunit RPABC5 | polymer | 67 | 7655.1 | 1 | UniProt (A0A8W4F9W9) Pfam (PF01194) | Sus scrofa (pig) | |
| 11 | K (K) | RNA polymerase II subunit J | polymer | 117 | 13310.3 | 1 | UniProt (A0A8D0TE17) Pfam (PF13656) | Sus scrofa (pig) | |
| 12 | L (L) | RNA polymerase II subunit K | polymer | 58 | 7018.2 | 1 | UniProt (A0A4X1TRS6) Pfam (PF03604) | Sus scrofa (pig) | |
| 13 | M (M) | Transcription elongation factor 1 homolog | polymer | 85 | 9616.9 | 1 | UniProt (A0A2K5RSX0) Pfam (PF05129) | Homo sapiens (human) | |
| 14 | N (N) | DNA (35-MER) | polymer | 90 | 27780.8 | 1 | synthetic construct | ||
| 15 | O (P) | RNA (5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3') | polymer | 10 | 3264.0 | 1 | synthetic construct | ||
| 16 | P (T) | DNA (49-MER) | polymer | 90 | 27551.6 | 1 | synthetic construct | ||
| 17 | Q (a) | DNA excision repair protein ERCC-8 | polymer | 396 | 44107.2 | 1 | UniProt (Q13216) Pfam (PF00400) | Homo sapiens (human) | Cockayne syndrome WD repeat protein CSA |
| 18 | R (b) | DNA excision repair protein ERCC-6 | polymer | 1496 | 168874.7 | 1 | UniProt (Q03468) Pfam (PF00176) Pfam (PF00271) | Homo sapiens (human) | ATP-dependent helicase ERCC6,Cockayne syndrome protein CSB |
| 19 | S (c) | UV-stimulated scaffold protein A | polymer | 712 | 80993.9 | 1 | UniProt (Q2YD98) Pfam (PF20867) Pfam (PF09740) | Homo sapiens (human) | |
| 20 | T (d) | DNA damage-binding protein 1 | polymer | 1143 | 127369.7 | 1 | UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) | Homo sapiens (human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
| 21 | U (e) | DET1- and DDB1-associated protein 1 | polymer | 105 | 12127.6 | 1 | UniProt (Q9BW61) Pfam (PF10172) | Homo sapiens (human) | Placenta cross-immune reaction antigen 1,PCIA-1 |
| 22 | V (f) | Inactive serine/threonine-protein kinase 19 | polymer | 254 | 28506.0 | 1 | UniProt (P49842) Pfam (PF10494) | Homo sapiens (human) | Protein G11,Protein RP1 |
| 23 | AA, BA, CA, DA, EA... (C, I, J, L, M...) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 24 | GA, Y (b, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 25 | IA (A) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
M: 2 - 83 (UniProt: A0A2K5RSX0)
b: 1 - 1493 (UniProt: Q03468)
c: 1 - 709 (UniProt: Q2YD98)
d: 1 - 1140 (UniProt: Q16531)
e: 1 - 102 (UniProt: Q9BW61)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Ala 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Gly 1213 | Arg 1213 | variant |
| Arg 1413 | Gln 1413 | variant |
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 22 |
| Total formula weight | 1057401.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 702.7 | |
| All* | Total formula weight | 1058103.9 |
