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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9BZ0

Structure of an STK19-containing TC-NER complex

Functional Information from GO Data
ChainGOidnamespacecontents
a0000012biological_processsingle strand break repair
a0000109cellular_componentnucleotide-excision repair complex
a0000209biological_processprotein polyubiquitination
a0005515molecular_functionprotein binding
a0005634cellular_componentnucleus
a0005654cellular_componentnucleoplasm
a0005694cellular_componentchromosome
a0005737cellular_componentcytoplasm
a0006283biological_processtranscription-coupled nucleotide-excision repair
a0006289biological_processnucleotide-excision repair
a0006974biological_processDNA damage response
a0006979biological_processresponse to oxidative stress
a0009411biological_processresponse to UV
a0010996biological_processresponse to auditory stimulus
a0016363cellular_componentnuclear matrix
a0016567biological_processprotein ubiquitination
a0031464cellular_componentCul4A-RING E3 ubiquitin ligase complex
a0031465cellular_componentCul4B-RING E3 ubiquitin ligase complex
a0032991cellular_componentprotein-containing complex
a0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
a0043204cellular_componentperikaryon
a0051865biological_processprotein autoubiquitination
a0080008cellular_componentCul4-RING E3 ubiquitin ligase complex
a0090262biological_processregulation of transcription-coupled nucleotide-excision repair
a0090734cellular_componentsite of DNA damage
a0097680biological_processdouble-strand break repair via classical nonhomologous end joining
a1990756molecular_functionubiquitin-like ligase-substrate adaptor activity
A0001172biological_processRNA-templated transcription
A0003677molecular_functionDNA binding
A0003899molecular_functionDNA-directed RNA polymerase activity
A0003968molecular_functionRNA-directed RNA polymerase activity
A0005634cellular_componentnucleus
A0005694cellular_componentchromosome
A0005737cellular_componentcytoplasm
A0006351biological_processDNA-templated transcription
A0006366biological_processtranscription by RNA polymerase II
b0000012biological_processsingle strand break repair
b0000077biological_processDNA damage checkpoint signaling
b0003677molecular_functionDNA binding
b0003678molecular_functionDNA helicase activity
b0003682molecular_functionchromatin binding
b0005515molecular_functionprotein binding
b0005524molecular_functionATP binding
b0005634cellular_componentnucleus
b0005654cellular_componentnucleoplasm
b0005694cellular_componentchromosome
b0005730cellular_componentnucleolus
b0006281biological_processDNA repair
b0006283biological_processtranscription-coupled nucleotide-excision repair
b0006284biological_processbase-excision repair
b0006338biological_processchromatin remodeling
b0006366biological_processtranscription by RNA polymerase II
b0006979biological_processresponse to oxidative stress
b0008023cellular_componenttranscription elongation factor complex
b0008094molecular_functionATP-dependent activity, acting on DNA
b0016604cellular_componentnuclear body
b0016887molecular_functionATP hydrolysis activity
b0022008biological_processneurogenesis
b0030182biological_processneuron differentiation
b0030296molecular_functionprotein tyrosine kinase activator activity
b0031175biological_processneuron projection development
b0032784biological_processregulation of DNA-templated transcription elongation
b0032786biological_processpositive regulation of DNA-templated transcription, elongation
b0034243biological_processregulation of transcription elongation by RNA polymerase II
b0042262biological_processDNA protection
b0045739biological_processpositive regulation of DNA repair
b0045943biological_processpositive regulation of transcription by RNA polymerase I
b0045944biological_processpositive regulation of transcription by RNA polymerase II
b0045945biological_processpositive regulation of transcription by RNA polymerase III
b0071168biological_processprotein localization to chromatin
b0090734cellular_componentsite of DNA damage
b0097680biological_processdouble-strand break repair via classical nonhomologous end joining
b0110016cellular_componentB-WICH complex
b0140463molecular_functionchromatin-protein adaptor activity
b0140658molecular_functionATP-dependent chromatin remodeler activity
b0140664molecular_functionATP-dependent DNA damage sensor activity
b1905168biological_processpositive regulation of double-strand break repair via homologous recombination
b2001033biological_processnegative regulation of double-strand break repair via nonhomologous end joining
B0001172biological_processRNA-templated transcription
B0003677molecular_functionDNA binding
B0003899molecular_functionDNA-directed RNA polymerase activity
B0003968molecular_functionRNA-directed RNA polymerase activity
B0005634cellular_componentnucleus
B0006351biological_processDNA-templated transcription
B0032549molecular_functionribonucleoside binding
B0034062molecular_function5'-3' RNA polymerase activity
c0000993molecular_functionRNA polymerase II complex binding
c0005515molecular_functionprotein binding
c0005634cellular_componentnucleus
c0005654cellular_componentnucleoplasm
c0005694cellular_componentchromosome
c0006283biological_processtranscription-coupled nucleotide-excision repair
c0006325biological_processchromatin organization
c0009411biological_processresponse to UV
c0016567biological_processprotein ubiquitination
c0090734cellular_componentsite of DNA damage
c0140463molecular_functionchromatin-protein adaptor activity
c0140870molecular_functionRNA polymerase inhibitor activity
C0003677molecular_functionDNA binding
C0003899molecular_functionDNA-directed RNA polymerase activity
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005665cellular_componentRNA polymerase II, core complex
C0006351biological_processDNA-templated transcription
C0006366biological_processtranscription by RNA polymerase II
C0006367biological_processtranscription initiation at RNA polymerase II promoter
C0006368biological_processtranscription elongation by RNA polymerase II
C0046983molecular_functionprotein dimerization activity
d0000109cellular_componentnucleotide-excision repair complex
d0000781cellular_componentchromosome, telomeric region
d0003676molecular_functionnucleic acid binding
d0003677molecular_functionDNA binding
d0003684molecular_functiondamaged DNA binding
d0005515molecular_functionprotein binding
d0005576cellular_componentextracellular region
d0005634cellular_componentnucleus
d0005654cellular_componentnucleoplasm
d0005730cellular_componentnucleolus
d0005737cellular_componentcytoplasm
d0006281biological_processDNA repair
d0006289biological_processnucleotide-excision repair
d0006511biological_processubiquitin-dependent protein catabolic process
d0006974biological_processDNA damage response
d0007056biological_processspindle assembly involved in female meiosis
d0007283biological_processspermatogenesis
d0008283biological_processcell population proliferation
d0010498biological_processproteasomal protein catabolic process
d0010506biological_processregulation of autophagy
d0016567biological_processprotein ubiquitination
d0019076biological_processviral release from host cell
d0030174biological_processregulation of DNA-templated DNA replication initiation
d0030674molecular_functionprotein-macromolecule adaptor activity
d0031297biological_processreplication fork processing
d0031464cellular_componentCul4A-RING E3 ubiquitin ligase complex
d0031465cellular_componentCul4B-RING E3 ubiquitin ligase complex
d0032814biological_processregulation of natural killer cell activation
d0032991cellular_componentprotein-containing complex
d0034644biological_processcellular response to UV
d0035861cellular_componentsite of double-strand break
d0040029biological_processepigenetic regulation of gene expression
d0042127biological_processregulation of cell population proliferation
d0042752biological_processregulation of circadian rhythm
d0042981biological_processregulation of apoptotic process
d0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
d0044725biological_processepigenetic programming in the zygotic pronuclei
d0044877molecular_functionprotein-containing complex binding
d0045070biological_processpositive regulation of viral genome replication
d0045722biological_processpositive regulation of gluconeogenesis
d0045732biological_processpositive regulation of protein catabolic process
d0045995biological_processregulation of embryonic development
d0046726biological_processpositive regulation by virus of viral protein levels in host cell
d0051702biological_processbiological process involved in interaction with symbiont
d0060964biological_processregulation of miRNA-mediated gene silencing
d0070062cellular_componentextracellular exosome
d0070914biological_processUV-damage excision repair
d0071987molecular_functionWD40-repeat domain binding
d0080008cellular_componentCul4-RING E3 ubiquitin ligase complex
d0080135biological_processregulation of cellular response to stress
d0097602molecular_functioncullin family protein binding
d0160072molecular_functionubiquitin ligase complex scaffold activity
d1901987biological_processregulation of cell cycle phase transition
d1901990biological_processregulation of mitotic cell cycle phase transition
d1902412biological_processregulation of mitotic cytokinesis
d1904178biological_processnegative regulation of adipose tissue development
d2000036biological_processregulation of stem cell population maintenance
D0000166molecular_functionnucleotide binding
D0006352biological_processDNA-templated transcription initiation
D0030880cellular_componentRNA polymerase complex
e0000209biological_processprotein polyubiquitination
e0005515molecular_functionprotein binding
e0005654cellular_componentnucleoplasm
e0016567biological_processprotein ubiquitination
e0031464cellular_componentCul4A-RING E3 ubiquitin ligase complex
e0031465cellular_componentCul4B-RING E3 ubiquitin ligase complex
e0032434biological_processregulation of proteasomal ubiquitin-dependent protein catabolic process
e0032436biological_processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
e0032814biological_processregulation of natural killer cell activation
e0080008cellular_componentCul4-RING E3 ubiquitin ligase complex
E0003677molecular_functionDNA binding
E0003899molecular_functionDNA-directed RNA polymerase activity
E0005634cellular_componentnucleus
E0005665cellular_componentRNA polymerase II, core complex
E0005666cellular_componentRNA polymerase III complex
E0005736cellular_componentRNA polymerase I complex
E0006351biological_processDNA-templated transcription
E0006362biological_processtranscription elongation by RNA polymerase I
E0006366biological_processtranscription by RNA polymerase II
E0042797biological_processtRNA transcription by RNA polymerase III
f0000993molecular_functionRNA polymerase II complex binding
f0003677molecular_functionDNA binding
f0003690molecular_functiondouble-stranded DNA binding
f0003723molecular_functionRNA binding
f0003725molecular_functiondouble-stranded RNA binding
f0004674molecular_functionprotein serine/threonine kinase activity
f0005515molecular_functionprotein binding
f0005634cellular_componentnucleus
f0005737cellular_componentcytoplasm
f0006282biological_processregulation of DNA repair
f0006283biological_processtranscription-coupled nucleotide-excision repair
f0008023cellular_componenttranscription elongation factor complex
f0016607cellular_componentnuclear speck
f0042803molecular_functionprotein homodimerization activity
f0046579biological_processpositive regulation of Ras protein signal transduction
f0062058molecular_functiontranscription factor TFIIH holo complex binding
f1903518biological_processpositive regulation of single strand break repair
F0001650cellular_componentfibrillar center
F0003677molecular_functionDNA binding
F0003899molecular_functionDNA-directed RNA polymerase activity
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005665cellular_componentRNA polymerase II, core complex
F0005666cellular_componentRNA polymerase III complex
F0005736cellular_componentRNA polymerase I complex
F0006351biological_processDNA-templated transcription
F0006360biological_processtranscription by RNA polymerase I
F0006362biological_processtranscription elongation by RNA polymerase I
F0006366biological_processtranscription by RNA polymerase II
F0006367biological_processtranscription initiation at RNA polymerase II promoter
F0006368biological_processtranscription elongation by RNA polymerase II
F0006383biological_processtranscription by RNA polymerase III
F0006384biological_processtranscription initiation at RNA polymerase III promoter
F0006386biological_processtermination of RNA polymerase III transcription
F0042797biological_processtRNA transcription by RNA polymerase III
G0003676molecular_functionnucleic acid binding
G0005634cellular_componentnucleus
G0006351biological_processDNA-templated transcription
G0006352biological_processDNA-templated transcription initiation
H0003899molecular_functionDNA-directed RNA polymerase activity
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005666cellular_componentRNA polymerase III complex
H0005736cellular_componentRNA polymerase I complex
H0006351biological_processDNA-templated transcription
I0001193biological_processmaintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
I0003676molecular_functionnucleic acid binding
I0003899molecular_functionDNA-directed RNA polymerase activity
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005665cellular_componentRNA polymerase II, core complex
I0005730cellular_componentnucleolus
I0006283biological_processtranscription-coupled nucleotide-excision repair
I0006351biological_processDNA-templated transcription
I0006366biological_processtranscription by RNA polymerase II
I0006367biological_processtranscription initiation at RNA polymerase II promoter
I0006368biological_processtranscription elongation by RNA polymerase II
I0008270molecular_functionzinc ion binding
J0003677molecular_functionDNA binding
J0003899molecular_functionDNA-directed RNA polymerase activity
J0005634cellular_componentnucleus
J0005665cellular_componentRNA polymerase II, core complex
J0005666cellular_componentRNA polymerase III complex
J0005736cellular_componentRNA polymerase I complex
J0006351biological_processDNA-templated transcription
J0006360biological_processtranscription by RNA polymerase I
J0006366biological_processtranscription by RNA polymerase II
J0008270molecular_functionzinc ion binding
J0042797biological_processtRNA transcription by RNA polymerase III
K0003677molecular_functionDNA binding
K0003899molecular_functionDNA-directed RNA polymerase activity
K0005634cellular_componentnucleus
K0005665cellular_componentRNA polymerase II, core complex
K0006351biological_processDNA-templated transcription
K0006366biological_processtranscription by RNA polymerase II
K0046983molecular_functionprotein dimerization activity
L0001650cellular_componentfibrillar center
L0003677molecular_functionDNA binding
L0003899molecular_functionDNA-directed RNA polymerase activity
L0005634cellular_componentnucleus
L0005654cellular_componentnucleoplasm
L0005665cellular_componentRNA polymerase II, core complex
L0005666cellular_componentRNA polymerase III complex
L0005730cellular_componentnucleolus
L0005736cellular_componentRNA polymerase I complex
L0006351biological_processDNA-templated transcription
L0006362biological_processtranscription elongation by RNA polymerase I
L0006366biological_processtranscription by RNA polymerase II
L0006367biological_processtranscription initiation at RNA polymerase II promoter
L0006368biological_processtranscription elongation by RNA polymerase II
L0006383biological_processtranscription by RNA polymerase III
L0006384biological_processtranscription initiation at RNA polymerase III promoter
L0006386biological_processtermination of RNA polymerase III transcription
L0008270molecular_functionzinc ion binding
M0000993molecular_functionRNA polymerase II complex binding
M0005634cellular_componentnucleus
M0006368biological_processtranscription elongation by RNA polymerase II
M0008023cellular_componenttranscription elongation factor complex
Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DNDPSDYVEqdDI
ChainResidueDetails
CASP136-ILE148
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YVCTAPH
ChainResidueDetails
ITYR112-HIS118
site_idPS00446
Number of Residues41
DetailsRNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSIRRvfiaevpiiAidwVqidaNsSvlhDEfIAhRLGLIP
ChainResidueDetails
CASN32-PRO72
site_idPS00466
Number of Residues38
DetailsZF_TFIIS_1 Zinc finger TFIIS-type signature. CqkCghkeavffqSHSARaEDAmrlyyvCtaph.CghrW
ChainResidueDetails
ICYS86-TRP123
site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. LATAsaDsRVKLWDV
ChainResidueDetails
aLEU202-VAL216
aLEU260-SER274
site_idPS01030
Number of Residues27
DetailsRNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCQECNNMLypkedkenrillyaCrnC
ChainResidueDetails
IPHE16-CYS42
site_idPS01110
Number of Residues14
DetailsRNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPEHvvMtkEE
ChainResidueDetails
EHIS142-GLU155
site_idPS01111
Number of Residues15
DetailsRNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARvLGtRAlQ
ChainResidueDetails
FTHR58-GLN72
site_idPS01112
Number of Residues10
DetailsRNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPVrCFTCG
ChainResidueDetails
JILE2-GLY11
site_idPS01154
Number of Residues32
DetailsRNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. InkEdHTLgNiIksqLlkdpqVlfagYkvpHP
ChainResidueDetails
KILE35-PRO66
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI26
Number of Residues25
DetailsZinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI27
Number of Residues42
DetailsZinc finger: {"description":"TFIIS-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI28
Number of Residues4
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10145","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI29
Number of Residues4
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI38
Number of Residues40
DetailsRepeat: {"description":"WD 1"}
ChainResidueDetails
site_idSWS_FT_FI39
Number of Residues41
DetailsRepeat: {"description":"WD 2"}
ChainResidueDetails
site_idSWS_FT_FI40
Number of Residues40
DetailsRepeat: {"description":"WD 3"}
ChainResidueDetails
site_idSWS_FT_FI41
Number of Residues39
DetailsRepeat: {"description":"WD 4"}
ChainResidueDetails
site_idSWS_FT_FI42
Number of Residues40
DetailsRepeat: {"description":"WD 6"}
ChainResidueDetails
site_idSWS_FT_FI43
Number of Residues38
DetailsRepeat: {"description":"WD 7"}
ChainResidueDetails
site_idSWS_FT_FI44
Number of Residues2
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI45
Number of Residues176
DetailsDomain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI46
Number of Residues159
DetailsDomain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI47
Number of Residues3
DetailsMotif: {"description":"DEAH box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI48
Number of Residues12
DetailsMotif: {"description":"CSA-interacting motif (CIM)","evidences":[{"source":"PubMed","id":"32355176","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI49
Number of Residues7
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI50
Number of Residues27
DetailsZinc finger: {"description":"UVSSA-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01403","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"38316879","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI51
Number of Residues9
DetailsCompositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails
site_idSWS_FT_FI52
Number of Residues4
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01403","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"38316879","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8B3D","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI53
Number of Residues46
DetailsRepeat: {"description":"WD 1","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI54
Number of Residues45
DetailsRepeat: {"description":"WD 2","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI55
Number of Residues51
DetailsRepeat: {"description":"WD 3","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI56
Number of Residues52
DetailsRepeat: {"description":"WD 4","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI57
Number of Residues44
DetailsRepeat: {"description":"WD 5","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI58
Number of Residues52
DetailsRepeat: {"description":"WD 6","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI59
Number of Residues46
DetailsRepeat: {"description":"WD 7","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI60
Number of Residues36
DetailsRepeat: {"description":"WD 8","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI61
Number of Residues43
DetailsRepeat: {"description":"WD 9","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI62
Number of Residues46
DetailsRepeat: {"description":"WD 10","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI63
Number of Residues40
DetailsRepeat: {"description":"WD 11","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI64
Number of Residues48
DetailsRepeat: {"description":"WD 12","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI65
Number of Residues49
DetailsRepeat: {"description":"WD 13","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI66
Number of Residues37
DetailsRepeat: {"description":"WD 14","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI67
Number of Residues34
DetailsRepeat: {"description":"WD 15","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9SFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI68
Number of Residues87
DetailsRepeat: {"description":"WD 16","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI69
Number of Residues60
DetailsRepeat: {"description":"WD 17","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI70
Number of Residues39
DetailsRepeat: {"description":"WD 18","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI71
Number of Residues42
DetailsRepeat: {"description":"WD 19","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI72
Number of Residues51
DetailsRepeat: {"description":"WD 20","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI73
Number of Residues40
DetailsRepeat: {"description":"WD 21","evidences":[{"source":"PubMed","id":"41565821","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9OTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OUL","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI74
Number of Residues766
DetailsRegion: {"description":"Interaction with CDT1","evidences":[{"source":"PubMed","id":"15448697","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI75
Number of Residues342
DetailsRegion: {"description":"WD40 beta-propeller A"}
ChainResidueDetails
site_idSWS_FT_FI76
Number of Residues360
DetailsRegion: {"description":"WD40 beta-propeller C"}
ChainResidueDetails
site_idSWS_FT_FI77
Number of Residues303
DetailsRegion: {"description":"WD40 beta-propeller B; Interaction with CUL4A"}
ChainResidueDetails
site_idSWS_FT_FI78
Number of Residues369
DetailsRegion: {"description":"Interaction with CDT1 and CUL4A","evidences":[{"source":"PubMed","id":"15448697","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI79
Number of Residues1
DetailsModified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI80
Number of Residues1
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI81
Number of Residues1
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q9ESW0","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI82
Number of Residues2
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI83
Number of Residues1
DetailsModified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI84
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI85
Number of Residues59
DetailsRegion: {"description":"Winged helix domain 2","evidences":[{"source":"PubMed","id":"38252411","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI86
Number of Residues74
DetailsRegion: {"description":"Winged helix domain 3","evidences":[{"source":"PubMed","id":"38252411","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

259693

PDB entries from 2026-09-16

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