9AVA
Co-crystal structure of human TREX1 in complex with an inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Three-prime repair exonuclease 1 | polymer | 231 | 24817.6 | 12 | UniProt (Q9NSU2) | Homo sapiens (human) | 3'-5' exonuclease TREX1,Deoxyribonuclease III,DNase III |
| 2 | AB, CA, EB, HB, JB... (I, D, J, K, L...) | POTASSIUM ION | non-polymer | 39.1 | 11 | Chemie (K) | |||
| 3 | BB, DA, FB, HA, IB... (I, D, J, E, K...) | (2R)-2-[(5R,6S,8R,9aS)-8-amino-1-oxo-5-(2-phenylethyl)hexahydro-1H-pyrrolo[1,2-a][1,4]diazepin-2(3H)-yl]-N-[(3,4-dichlorophenyl)methyl]-4-methylpentanamide | non-polymer | 545.5 | 12 | Chemie (A1AG1) | |||
| 4 | AA, BA, CB, DB, EA... (C, I, D, J, E...) | UNKNOWN ATOM OR ION | non-polymer | 29 | Chemie (UNX) | ||||
| 5 | MB, NB, OB, PB, QB... (A, B, C, D, E...) | water | water | 18.0 | 669 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 5 - 234 (UniProt: Q9NSU2)
| PDB | External Database | Details |
|---|---|---|
| Gly 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 297810.7 | |
| Non-Polymers* | Number of molecules | 52 |
| Total formula weight | 6976.6 | |
| All* | Total formula weight | 304787.3 |
