9AVA

Co-crystal structure of human TREX1 in complex with an inhibitor

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0008408	molecular_function	3'-5' exonuclease activity
B	0003676	molecular_function	nucleic acid binding
B	0008408	molecular_function	3'-5' exonuclease activity
C	0003676	molecular_function	nucleic acid binding
C	0008408	molecular_function	3'-5' exonuclease activity
D	0003676	molecular_function	nucleic acid binding
D	0008408	molecular_function	3'-5' exonuclease activity
E	0003676	molecular_function	nucleic acid binding
E	0008408	molecular_function	3'-5' exonuclease activity
F	0003676	molecular_function	nucleic acid binding
F	0008408	molecular_function	3'-5' exonuclease activity
G	0003676	molecular_function	nucleic acid binding
G	0008408	molecular_function	3'-5' exonuclease activity
H	0003676	molecular_function	nucleic acid binding
H	0008408	molecular_function	3'-5' exonuclease activity
I	0003676	molecular_function	nucleic acid binding
I	0008408	molecular_function	3'-5' exonuclease activity
J	0003676	molecular_function	nucleic acid binding
J	0008408	molecular_function	3'-5' exonuclease activity
K	0003676	molecular_function	nucleic acid binding
K	0008408	molecular_function	3'-5' exonuclease activity
L	0003676	molecular_function	nucleic acid binding
L	0008408	molecular_function	3'-5' exonuclease activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"UniProtKB","id":"Q91XB0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q91XB0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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