8ZRT
Cryo-EM structure focused on the receptor of the ET-1 bound ETBR-DNGI complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Endothelin receptor type B | polymer | 346 | 38808.3 | 1 | UniProt (P24530) Pfam (PF00001) | Homo sapiens (human) | ET-B,ET-BR,Endothelin receptor non-selective type |
| 2 | B (L) | Endothelin-1 | polymer | 21 | 2498.0 | 1 | UniProt (P05305) Pfam (PF00322) | Homo sapiens (human) | Preproendothelin-1,PPET1 |
Sequence modifications
R: 66 - 407 (UniProt: P24530)
| PDB | External Database | Details |
|---|---|---|
| Pro 62 | - | expression tag |
| Gly 63 | - | expression tag |
| Gly 64 | - | expression tag |
| Gly 65 | - | expression tag |
| Tyr 124 | Arg 124 | conflict |
| Ala 396 | Cys 396 | conflict |
| Ala 400 | Cys 400 | conflict |
| Ala 405 | Cys 405 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41306.2 | |
| All* | Total formula weight | 41306.2 |
