8YQ0
Crystal structure of human phosphoribosyl pyrophosphate synthetase 1(PRPS1) chimera swapped with three residues from PRPS2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ribose-phosphate pyrophosphokinase 1 | polymer | 321 | 35120.4 | 18 | UniProt (P60891) Pfam (PF13793) Pfam (PF14572) | Homo sapiens (human) | PPRibP,Phosphoribosyl pyrophosphate synthase I,PRS-I |
| 2 | S, T, U (B, F, O) | 5-O-phosphono-alpha-D-ribofuranose | non-polymer | 230.1 | 3 | Chemie (HSX) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R: 2 - 321 (UniProt: P60891)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Val 103 | - | insertion |
| Gly 104 | - | insertion |
| Glu 105 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 632167.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 690.3 | |
| All* | Total formula weight | 632857.9 |
