8YPY
Crystal strcuture of human phosphoribosyl pyrophosphate synthetase2 (PRPS2) in complex with ligands
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Isoform 2 of Ribose-phosphate pyrophosphokinase 2 | polymer | 321 | 35053.3 | 6 | UniProt (P11908) Pfam (PF13793) Pfam (PF14572) | Homo sapiens (human) | PPRibP,Phosphoribosyl pyrophosphate synthase II,PRS-II |
| 2 | G, J, P, Q, T... (A, C, D, E) | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | non-polymer | 505.2 | 6 | Chemie (APC) | |||
| 3 | AA, H, N, R, U... (F, A, B, C, D...) | 5-O-phosphono-alpha-D-ribofuranose | non-polymer | 230.1 | 6 | Chemie (HSX) | |||
| 4 | BA, I, O, S, V... (F, A, B, C, D...) | CADMIUM ION | non-polymer | 112.4 | 6 | Chemie (CD) | |||
| 5 | CA, K, L, M, W (F, A, D) | PHOSPHATE ION | non-polymer | 95.0 | 5 | Chemie (PO4) | |||
| 6 | DA, EA, FA, GA, HA... (A, B, C, D, E...) | water | water | 18.0 | 191 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 2 - 321 (UniProt: P11908)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 210319.7 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 5561.2 | |
| All* | Total formula weight | 215880.9 |
