8YPY

Crystal strcuture of human phosphoribosyl pyrophosphate synthetase2 (PRPS2) in complex with ligands

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004749	molecular_function	ribose phosphate diphosphokinase activity
A	0009156	biological_process	ribonucleoside monophosphate biosynthetic process
A	0009165	biological_process	nucleotide biosynthetic process
B	0000287	molecular_function	magnesium ion binding
B	0004749	molecular_function	ribose phosphate diphosphokinase activity
B	0009156	biological_process	ribonucleoside monophosphate biosynthetic process
B	0009165	biological_process	nucleotide biosynthetic process
C	0000287	molecular_function	magnesium ion binding
C	0004749	molecular_function	ribose phosphate diphosphokinase activity
C	0009156	biological_process	ribonucleoside monophosphate biosynthetic process
C	0009165	biological_process	nucleotide biosynthetic process
D	0000287	molecular_function	magnesium ion binding
D	0004749	molecular_function	ribose phosphate diphosphokinase activity
D	0009156	biological_process	ribonucleoside monophosphate biosynthetic process
D	0009165	biological_process	nucleotide biosynthetic process
E	0000287	molecular_function	magnesium ion binding
E	0004749	molecular_function	ribose phosphate diphosphokinase activity
E	0009156	biological_process	ribonucleoside monophosphate biosynthetic process
E	0009165	biological_process	nucleotide biosynthetic process
F	0000287	molecular_function	magnesium ion binding
F	0004749	molecular_function	ribose phosphate diphosphokinase activity
F	0009156	biological_process	ribonucleoside monophosphate biosynthetic process
F	0009165	biological_process	nucleotide biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00114
Number of Residues	16
Details	PRPP_SYNTHASE Phosphoribosyl pyrophosphate synthase signature. DLHAsQIQGFFdiPVD

Chain	Residue	Details
A	ASP131-ASP146

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	75
Details	Region: {"description":"Binding of phosphoribosylpyrophosphate","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	20
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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