8YHR

DHODH in complex with furocoumavirin

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Dihydroorotate dehydrogenase (quinone), mitochondrial	polymer	387	42027.9	1	UniProt (Q02127) Pfam (PF01180) In PDB	Homo sapiens (human)	DHOdehase,Dihydroorotate oxidase
2	A	OROTIC ACID	non-polymer		156.1	1	Chemie (ORO)
3	A	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	1	Chemie (FMN)
4	A	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5	A	ACETATE ION	non-polymer		59.0	5	Chemie (ACT)
6	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
7	A	4-methyl-8-[(S)-oxidanyl(phenyl)methyl]-9-phenyl-furo[2,3-h]chromen-2-one	non-polymer		382.4	1	Chemie (A1LYU)
8		water	water		18.0	270	Chemie (HOH)

Sequence modifications

A: 29 - 395 (UniProt: Q02127)

PDB	External Database	Details
Met 9	-	initiating methionine
Gly 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
Ser 19	-	expression tag
Ser 20	-	expression tag
Gly 21	-	expression tag
Leu 22	-	expression tag
Val 23	-	expression tag
Pro 24	-	expression tag
Arg 25	-	expression tag
Gly 26	-	expression tag
Ser 27	-	expression tag
His 28	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42027.9
Non-Polymers*	Number of molecules	12
	Total formula weight	1662.4
All*	Total formula weight	43690.3

*Water molecules are not included.