8YHL
The Crystal Structure of Tgf-Beta Type I Receptor (Alk5) from Biortus
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TGF-beta receptor type-1 | polymer | 306 | 34939.2 | 1 | UniProt (P36897) Pfam (PF00069) In PDB | Homo sapiens (human) | TGFR-1,Activin A receptor type II-like protein kinase of 53kD,Activin receptor-like kinase 5,ALK-5,ALK5,Serine/threonine-protein kinase receptor R4,SKR4,TGF-beta type I receptor,Transforming growth factor-beta receptor type I,TGF-beta receptor type I,TbetaR-I |
| 2 | A | 2-fluoranyl-~{N}-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1~{H}-imidazol-2-yl]methyl]aniline | non-polymer | 399.4 | 1 | Chemie (A1D6I) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | A | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A: 200 - 503 (UniProt: P36897)
| PDB | External Database | Details |
|---|---|---|
| Gly 198 | - | expression tag |
| Gly 199 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34939.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 641.6 | |
| All* | Total formula weight | 35580.8 |
