8Y6B
Structure of human LGI1-ADAM22 complex in space group P212121
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D (A, B, C) | Disintegrin and metalloproteinase domain-containing protein 22 | polymer | 486 | 53743.1 | 3 | UniProt (Q9P0K1) Pfam (PF01421) Pfam (PF00200) Pfam (PF08516) Pfam (PF07974) | Homo sapiens (human) | ADAM 22,Metalloproteinase-disintegrin ADAM22-3,Metalloproteinase-like,disintegrin-like,and cysteine-rich protein 2 |
| 2 | B, E, F (D, F, E) | Leucine-rich glioma-inactivated protein 1 | polymer | 526 | 60616.6 | 3 | UniProt (O95970) Pfam (PF03736) Pfam (PF13855) | Homo sapiens (human) | Epitempin-1 |
| 3 | CA, DA, EA, G, GA... (F, A, E, D, B...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 18 | Chemie (NAG) | |||
| 4 | AA, BA, FA, J, JA... (C, F, A, E, D...) | CALCIUM ION | non-polymer | 40.1 | 12 | Chemie (CA) | |||
| 5 | KA, LA, MA, NA, OA... (A, D, B, C, F...) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
D, F, E: 39 - 557 (UniProt: O95970)
| PDB | External Database | Details |
|---|---|---|
| His 32 | - | expression tag |
| His 33 | - | expression tag |
| His 34 | - | expression tag |
| His 35 | - | expression tag |
| His 36 | - | expression tag |
| His 37 | - | expression tag |
| His 38 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 343079.1 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 4462.7 | |
| All* | Total formula weight | 347541.8 |
