8XOX
The Crystal Structure of FAK2 from Biortus.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Protein-tyrosine kinase 2-beta | polymer | 277 | 32190.3 | 1 | UniProt (Q14289) Pfam (PF07714) | Homo sapiens (human) | Calcium-dependent tyrosine kinase,CADTK,Calcium-regulated non-receptor proline-rich tyrosine kinase,Cell adhesion kinase beta,CAK-beta,CAKB,Focal adhesion kinase 2,FADK 2,Proline-rich tyrosine kinase 2,Related adhesion focal tyrosine kinase,RAFTK |
2 | B (A) | N-methyl-N-{3-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide | non-polymer | 507.5 | 1 | Chemie (YAM) | |||
3 | C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
4 | F (A) | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 32190.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 693.7 | |
All* | Total formula weight | 32884.0 |