8XOX
The Crystal Structure of FAK2 from Biortus.
Functional Information from GO Data
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 27 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGFFGEVYeGvytnhkgekin.......VAVK |
| Chain | Residue | Details |
| A | LEU431-LYS457 |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CVHrDIAVRNILV |
| Chain | Residue | Details |
| A | CYS545-VAL557 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10028 |
| Chain | Residue | Details |
| A | ASP549 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19244237, ECO:0007744|PDB:3FZP |
| Chain | Residue | Details |
| A | LEU431 | |
| A | LYS457 | |
| A | GLU503 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q9QVP9 |
| Chain | Residue | Details |
| A | TYR579 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by SRC, FYN and LCK => ECO:0000269|PubMed:20028775, ECO:0000269|PubMed:20381867 |
| Chain | Residue | Details |
| A | TYR580 |
