8XJZ
Cryo-EM structure of colibactin assembly line polyketide synthase ClbI KS-AT didomain crosslinked with its precursor module, ClbH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Polyketide synthase | polymer | 921 | 99125.7 | 2 | UniProt (Q0P7J9) | Escherichia coli | Putative polyketide synthase |
| 2 | C (C) | Peptide synthetase | polymer | 1634 | 180781.8 | 1 | UniProt (Q0P7J8) | Escherichia coli | Putative non-ribosomal peptide synthase |
| 3 | D (D) | polypeptide from ClbH | polymer | 26 | 2230.7 | 1 | Escherichia coli |
Sequence modifications
A, B: 1 - 895 (UniProt: Q0P7J9)
C: 1 - 1598 (UniProt: Q0P7J8)
| PDB | External Database | Details |
|---|---|---|
| Lys 896 | - | expression tag |
| Leu 897 | - | expression tag |
| Ser 898 | - | expression tag |
| Ser 899 | - | expression tag |
| Gly 900 | - | expression tag |
| Leu 901 | - | expression tag |
| Glu 902 | - | expression tag |
| Val 903 | - | expression tag |
| Leu 904 | - | expression tag |
| Phe 905 | - | expression tag |
| Gln 906 | - | expression tag |
| Gly 907 | - | expression tag |
| Pro 908 | - | expression tag |
| Ser 909 | - | expression tag |
| Ser 910 | - | expression tag |
| Gly 911 | - | expression tag |
| His 912 | - | expression tag |
| His 913 | - | expression tag |
| His 914 | - | expression tag |
| His 915 | - | expression tag |
| His 916 | - | expression tag |
| His 917 | - | expression tag |
| His 918 | - | expression tag |
| His 919 | - | expression tag |
| His 920 | - | expression tag |
| His 921 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -35 | - | initiating methionine |
| Gly -34 | - | expression tag |
| Ser -33 | - | expression tag |
| Ser -32 | - | expression tag |
| His -31 | - | expression tag |
| His -30 | - | expression tag |
| His -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| Ser -25 | - | expression tag |
| Ser -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Leu -22 | - | expression tag |
| Val -21 | - | expression tag |
| Pro -20 | - | expression tag |
| Arg -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| His -16 | - | expression tag |
| Met -15 | - | expression tag |
| Ala -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Met -12 | - | expression tag |
| Thr -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Gln -8 | - | expression tag |
| Gln -7 | - | expression tag |
| Met -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Arg -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 381264.0 | |
| All* | Total formula weight | 381264.0 |
