8XJZ

Cryo-EM structure of colibactin assembly line polyketide synthase ClbI KS-AT didomain crosslinked with its precursor module, ClbH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
C	0003824	molecular_function	catalytic activity
C	0005737	cellular_component	cytoplasm
C	0016874	molecular_function	ligase activity
C	0016877	molecular_function	ligase activity, forming carbon-sulfur bonds
C	0031177	molecular_function	phosphopantetheine binding
C	0043041	biological_process	amino acid activation for nonribosomal peptide biosynthetic process
C	0044550	biological_process	secondary metabolite biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00455
Number of Residues	12
Details	AMP_BINDING Putative AMP-binding domain signature. IIYTSGSTGvPK

Chain	Residue	Details
C	ILE157-LYS168
C	VAL1132-LYS1143

---