8XGY
Crystal structure of human Golgi resident glutaminyl cyclase in complex with (R,Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-((1-acetylpyrrolidin-3-yl)oxy)indolin-2-one
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (B, A, C, D, E...) | Glutaminyl-peptide cyclotransferase | polymer | 329 | 37557.4 | 12 | UniProt (Q16769) Pfam (PF04389) | Homo sapiens (human) | Glutaminyl cyclase,QC,sQC,Glutaminyl-tRNA cyclotransferase,Glutamyl cyclase,EC |
| 2 | AA, CA, EA, GA, IA... (H, I, J, K, L...) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 3 | BA, DA, FA, HA, JA... (H, I, J, K, L...) | (3~{Z})-3-(1~{H}-benzimidazol-5-ylmethylidene)-4-[(3~{R})-1-ethanoylpyrrolidin-3-yl]oxy-1~{H}-indol-2-one | non-polymer | 388.4 | 12 | Chemie (A1D5C) | |||
| 4 | KA, LA, MA, NA, OA... (B, A, C, D, E...) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 450688.8 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 5445.9 | |
| All* | Total formula weight | 456134.7 |
