8XGY

Crystal structure of human Golgi resident glutaminyl cyclase in complex with (R,Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-((1-acetylpyrrolidin-3-yl)oxy)indolin-2-one

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A, C, D, E...	Glutaminyl-peptide cyclotransferase	polymer	329	37557.4	12	UniProt (Q16769) Pfam (PF04389) In PDB	Homo sapiens (human)	Glutaminyl cyclase,QC,sQC,Glutaminyl-tRNA cyclotransferase,Glutamyl cyclase,EC
2	H, I, J, K, L...	ZINC ION	non-polymer		65.4	12	Chemie (ZN)
3	H, I, J, K, L...	(3~{Z})-3-(1~{H}-benzimidazol-5-ylmethylidene)-4-[(3~{R})-1-ethanoylpyrrolidin-3-yl]oxy-1~{H}-indol-2-one	non-polymer		388.4	12	Chemie (A1D5C)
4		water	water		18.0	21	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	450688.8
Non-Polymers*	Number of molecules	24
	Total formula weight	5445.9
All*	Total formula weight	456134.7

*Water molecules are not included.