8X94

Structure of human TRPV1 in complex with antagonist --protein purified without CHS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Transient receptor potential cation channel subfamily V member 1,Green fluorescent protein	polymer	1112	125297.7	4	UniProt (Q8NER1) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520)	Homo sapiens (human)	TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1
2	E, G, I, K (A, B, C, D)	4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile	non-polymer		305.3	4	Chemie (EZI)
3	F, H, J, L (A, B, C, D)	CHOLESTEROL	non-polymer		386.7	4	Chemie (CLR)

Sequence modifications

A, B, C, D: 1 - 839 (UniProt: Q8NER1)
A, B, C, D: 840 - 1112 (PDB: 8X94)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	501190.9
Non-Polymers*	Number of molecules	8
	Total formula weight	2767.9
All*	Total formula weight	503958.9

*Water molecules are not included.