8X94

Structure of human TRPV1 in complex with antagonist --protein purified without CHS

Summary for 8X94

• Entry DOI: 10.2210/pdb8x94/pdb
• EMDB information: 38161
• Descriptor: Transient receptor potential cation channel subfamily V member 1,Green fluorescent protein, 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile, CHOLESTEROL (3 entities in total)
• Functional Keywords: channel, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 503958.88

Authors

Fan, J.,Lei, X. (deposition date: 2023-11-29, release date: 2024-08-14)

• Primary citation: Fan, J.,Ke, H.,Lei, J.,Wang, J.,Tominaga, M.,Lei, X.; Structural basis of TRPV1 inhibition by SAF312 and cholesterol; Nat Commun, 15:6689-, 2024; DOI: 10.1038/s41467-024-51085-3

Experimental method