8W6P

Crystal structure of dimeric murine SMPDL3A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Acid sphingomyelinase-like phosphodiesterase 3a	polymer	413	46664.6	2	UniProt (P70158) Pfam (PF00149) Pfam (PF19272) In PDB	Mus musculus (house mouse)	ASM-like phosphodiesterase 3a
2	C, E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
3	D	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	1	In PDB GlyTouCan (G86851RC)
4	F	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	A	[(2~{R},3~{S},4~{S})-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphinic acid	non-polymer		230.2	1	Chemie (YA4)
6	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
7	A, B	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
8	B	alpha-L-fucopyranose	non-polymer		164.2	1	Chemie (FUC)
9	B	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
10		water	water		18.0	804	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	93329.2
Branched	Number of molecules	4
	Total formula weight	1802.7
Non-Polymers*	Number of molecules	13
	Total formula weight	2078.2
All*	Total formula weight	97210.1

*Water molecules are not included.