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8W0V

Crystal structure of broadly neutralizing antibody hcab55 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
Envelope glycoprotein E2polymer26228946.51UniProt (A0A2P0NE15)
Pfam (PF01560)
UniProt (by SIFTS) (A0A2P0NE26)
Hepacivirus hominis
2B
(H)
hcab55 Fab Heavy Chainpolymer23725447.61Homo sapiens
3C
(L)
hcab55 Fab Light Chainpolymer21523528.21Homo sapiens
4D
(A)
alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.71In PDB
GlyTouCan (G22573RC)
5E, F
(B, D)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.42In PDB
GlyTouCan (G42666HT)
6G
(E)
alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.71In PDB
GlyTouCan (G81315DD)
7H
(C)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight77922.2
BranchedNumber of molecules4
Total formula weight2346.2
Non-Polymers*Number of molecules1
Total formula weight221.2
All*Total formula weight80489.6
*Water molecules are not included.

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PDB entries from 2024-11-06

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